By Yuriy Brun (auth.), Yasubumi Sakakibara, Yongli Mi (eds.)
This ebook constitutes the completely refereed post-conference
proceedings of the sixteenth foreign convention on DNA Computing and Molecular Programming, DNA16, held in Hong Kong, China, in June 2010.
The sixteen revised complete papers offered have been rigorously chosen in the course of rounds of reviewing and development from fifty nine submissions. The papers are good balanced among theoretical and experimental paintings and handle all components that relate to biomolecular computing, together with demonstrations of biomolecular computing, theoretical versions of biomolecular computing, biomolecular algorithms, computational strategies in vitro and in vivo, research and theoretical types of laboratory innovations, biotechnological and different functions of DNA computing, DNA nanostructures, DNA units similar to DNA automobiles, DNA errors review and correction, in vitro evolution, molecular layout, self-assembled platforms, nucleic acid chemistry, and simulation tools.
Read Online or Download DNA Computing and Molecular Programming: 16th International Conference, DNA 16, Hong Kong, China, June 14-17, 2010, Revised Selected Papers PDF
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Extra resources for DNA Computing and Molecular Programming: 16th International Conference, DNA 16, Hong Kong, China, June 14-17, 2010, Revised Selected Papers
Signal Restoration Gate Reactions: The NAND and fan-out gates contain no digital abstraction: each input species “pushes” on the output in linear proportion to the concentration of the input. g. 1), then the best the output could be is 90% ideal. In reality, even this is not achieved since our DNA strand displacement implementation of the reactions introduces some non-idealities that imply there will be signal loss at each logical gate. The signal restoration gate described below functions to restore the signal.
The conversion of an example circuit is shown in Figure 2. We choose NAND gates for the sake of concreteness, but it is easy to modify our design to implement any of the sixteen possible 2-input/1-output logic gates. Our design of the three gates is described in terms of sets of abstract chemical reactions implemented by DNA strand displacement in a similar fashion Scalable, Time-Responsive, Digital, Energy-Eﬃcient Molecular Circuits i1 i2 29 i1 i2 i3 i2 i3 i2 i2 i1 NAND FANOUT i2 i3 SIGNAL RESTORATION Fig.
Whenever the termolecular reaction completes successfully, the numbers of buﬀer1 and buﬀer2 increase by 1. Unless processed properly these buﬀers accumulate and become more and more competitive against A and B. For the buﬀer1 strand, this problem may be solved by having the gate g1 and buﬀer1 be in excess such that their concentrations remain eﬀectively constant; this is the trick used in . However, this argument does not apply to buﬀer2, since buﬀer2 reacts with g1 : A complexes. The number of these is necessarily no larger than the number of A strands, no matter how many gate complexes g1 are supplied.
DNA Computing and Molecular Programming: 16th International Conference, DNA 16, Hong Kong, China, June 14-17, 2010, Revised Selected Papers by Yuriy Brun (auth.), Yasubumi Sakakibara, Yongli Mi (eds.)