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One of the requirements of a perfusion solution is that it must be iso-osmotic with the intracellular fluid. The addition of 5–10% low MW dextran has proved beneficial in preserving isoosmolality and good results have been obtained with kidney, liver, and cornea perfusions (243–247). 8. Debrisan Debrisan™ is a wound-cleansing agent prepared in bead form by the emulsion polymerization of dextran with epichlorohydrin. The product acts by absorbing (approx. 4 ml/g) wound exudate in secreting, infected wounds, ulcers and sores, thereby shortening the healing time.

Med. 75, 339 (1942). 153. Schenk, G. Thesis, Univ. of Munich, 1962. 154. W. F. Biochim. Biophys. Acta 785, 89 (1984). 155. Monsan, P. and Lopez, A. Biotechnol. Bioeng. 23, 2027 (1981). 156. Braswell, E. et al. J. Polym. Sci. 61, 143 (1962). 157. Brock Neely, W. J. Am. Chem. Soc. 81, 4416 (1959). 158. Jeanes, A. et al. Arch. Biochem. Biophys. 71, 293 (1957). 159. Sabatie, J. et al. Carbohydr. Polym. 9, 87 (1988). 160. Sabatie, J. et al. Biotech. Lett. 8, 425 (1986). 161. Braswell, E. G. J. Polym.

Transplantation 25, 92 (1978). 247. A. et al. Arch. Ophthalmol. 97, 153 (1979). 248. Rothman, U. Personal communication. 1984. 249. Jacobsson, S. and Rothman, U. I. R. C. S. 11, 3117 (1973). 250. Jacobsson, S. et al. Scand. J. Plast. Reconstr. Surg. 10, 65 (1976). 251. W. et al. Clinical Trials J. 22, 432 (1985). 252. G. et al. J. Postgrad. Med. 31, 28 (1985). 253. Åkesson, Å. and Friman, G. Clin. Trials J. 21, 378 (1984). 254. K. S. Clin. Obstet. Gynecol. 26, 277 (1983). 255. J. et al. Fertil.

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Dextran by Amersham Bioscience


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