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Download e-book for kindle: Cell Culture and its Application by Ronald T. Acton

By Ronald T. Acton

ISBN-10: 0120430509

ISBN-13: 9780120430505

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Additional resources for Cell Culture and its Application

Example text

Springer-Verlag, Berlin, (in press). Seeds, N. , Gilman, A. , (1971), Science 174, 292. Seeds, N. , Haffke, S. C , (1976), submitted for publication. Seeds, N. , Vatter, Α. , (1971), Proc. Nat. Acad. Sei. A. 68, 3219-3222. Sidman, R. , (1974), in "The Cell Surface in Development," (A. Moscona, e d . ) , pp. 221-253, J. Wiley, New York. Yamamura, Η. , Synder, S. H. (1974), Proc. Nat. Acad. Sei. A. 71, 1725-1729. DIFFERENTIATION OF Τ CELLS IN VITRO GIDEON GOLDSTEIN Memorial Sloan-Kettering Cancer Center New York, New York Thymus derived lymphocytes (T cells) represent a population of cells that is replenished by differentiation of precursor cells, even in the adult organism.

Cell matura- tion in vivo appears to require that precursor cells interact with thymic epithelium. Dr. Goldstein has demonstrated that thymo- poietin, a protein extracted from the thymus and now purified to homogeneity, induces in Τ cell precursors membrane changes associated with maturation. This implies that at least certain thy- mic functions are mediated by a hormone, and has made possible investigation of the biochemical basis of the differentiation process. Dr. Papaconstantinou induces hemoglobin synthesis by treating Friend leukemia cells with dimethylsulfoxide.

Moscona, e d . ) , pp. 221-253, J. Wiley, New York. Yamamura, Η. , Synder, S. H. (1974), Proc. Nat. Acad. Sei. A. 71, 1725-1729. DIFFERENTIATION OF Τ CELLS IN VITRO GIDEON GOLDSTEIN Memorial Sloan-Kettering Cancer Center New York, New York Thymus derived lymphocytes (T cells) represent a population of cells that is replenished by differentiation of precursor cells, even in the adult organism. Thus a lineage has been traced whereby thymocyte precursors originate in the hemopoetic tissue and migrate to thymus, differentiating therein to thymocytes.

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Cell Culture and its Application by Ronald T. Acton


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